LONDON - Outraged celebrities tore into Italian fashion designers Domenico Dolce and Stefano Gabbana on Monday after Dolce described children born to gay couples through fertility treatment as "synthetic".
Pop superstar Elton John, leading the chorus of criticism, called for a boycott of the brand on Sunday.
Victoria Beckham, a former Dolce and Gabbana ambassador, offered John sympathy on Monday, sending a "message of love" to the singer, his husband partner David Furnish and their two sons Zachary and Elijah, and to "all the beautiful IVF babies".
Rock star Courtney Love accused the Italian pair of "senseless bigotry".
But Gabbana dug his heels in, saying they were entitled to their opinion and calling John a fascist.
An industry expert doubted any boycott call would have any effect.
Concetta Lanciaux, a luxury industry consultant and former adviser to Bernard Arnault, CEO and founder of luxury group LVMH, said she did not think John's boycott demand would have an impact on D&G's sales.
"Consumers understand the humour of Domenico and Stefano, who are known for their wit. In addition, new consumers, even if they do not agree with the statement, like to think we live in a free world where people still can express their feelings and opinions," she said.
The furor erupted after Italian magazine Panorama quoted Sicilian-born Dolce as criticising fertility treatment and same-sex parenting.
"You are born and you have a father and a mother. Or at least it should be like this, that's why I am not convinced by chemical children, synthetic babies, wombs for rent," Dolce said.
John responded angrily, vowing to never wear Dolce and Gabbana clothes again.
"How dare you refer to my beautiful children as 'synthetic'. And shame on you for wagging your judgmental little fingers at IVF ... Your archaic thinking is out of step with the times, just like your fashions," John said.
Friends and celebrities from the acting, fashion and music world rallied to the cause.
Love said in her tweet: "Just round up all my Dolce & Gabbana pieces, I want to burn them ... boycott senseless bigotry!"