In a ground-breaking discovery, A*STAR scientists have found a metabolic pathway in the body that controls obesity, atherosclerosis and maybe even cancer.
The scientists, from the Institute of Molecular and Cell Biology and the Singapore Bioimaging Consortium, showed, for the first time, that mice deficient in the Wip1 gene were resistant to weight gain and atherosclerosis, which is the hardening of arteries.
The scientists hope the pathway could similarly map onto cancer to suppress tumour progression. The findings were published in the journal Cell Metabolism on July 3.
This article was first published in The New Paper.