Kathy Griffin suggests President Donald Trump be injected with potentially fatal syringe

Kathy Griffin has sparked outrage after suggesting President Donald Trump be injected with a potentially-fatal syringe.

The outspoken comedienne - who caused a huge backlash in 2017 when she tweeted an image of herself and what looked like the bloodied head of the president - suggested the US leader be subjected to an injection of "nothing but air", a procedure that could cause a lethal blood vessel blockage caused by bubbles or air or gas in the circulatory system.

Kathy was responding to a tweet that said the president had been at a White House diabetes event, and asked: "I don't use insulin. Should I be?"

She replied: "Syringe with nothing but air inside it would do the trick. F*** TRUMP. (sic)"

The Washington Examiner newspaper pointed out the action could be fatal but Kathy remained defiant.

The paper's account posted: "@KathyGriffin advocates for someone to stab @realDonaldTrump with syringe full of air.

"Air embolisms, caused by air getting into the bloodstream, can be fatal."

Kathy replied: "I SURE DID, F---ER. (sic)"

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After her controversial photoshoot with the Trump head, the 59-year-old star lost endorsements deals, her tour was axed, and she was dropped from her role as co-host of CNN's New Year's Eve coverage with Anderson Cooper.

The star was also put on the no-fly list until the FBI investigation into her was completed.

She previously said: "Trust me, there are times when I want to distance myself from that photo, but it really is a First Amendment issue.

"They were thinking of charging me with conspiracy to assassinate the President of the United States, because I look like the typical ISIS member, right?"

And she was also sent death threats as a result of the controversial pictures.

She said: "I admit for two days I was on a ball on the floor sobbing and yes, I had a horrible press conference and all that other stuff made it worse... everyone turned on me, left and right.

"On the one hand, I was being investigated by the feds, and on the other hand, I was getting calls from the FBI saying, 'OK, you're under a legitimate and what they say credible threat,' so a lot has happened."